Plug in Baby

"Plug in Baby" is about evolution in the wake of modern technology. Speaking to Rock Sound in 2001 about the song's meaning, lead singer and guitarist Matt Bellamy said: "There's the good side and the bad side [to technology]; abandoning all individuality, becoming a collective whole via cables, and genetically engineering bodies that can exist out in space, or the loss of individualism."

Matt Bellamy used a Hugh Manson custom electric guitar, with a built-in Z Vex Fuzz Factory set for the classical-influenced intro riff. The song helped Bellamy establish himself as one of the most innovative guitarists of his generation.

On the show Muse: The Making of Origin of Symmetry, which aired on the UK radio station Xfm, Matthew Bellamy described this song as: "A feeling of not being connected to each other, but we are, and it's a feeling of the mind evolving from the body, but when that happens you just get this yearn to do something physical and feel something sensational."