Interpretation #1: Like most of the songs on the album Nevermind, this is about Kurt Cobain's life in and around Olympia, Washington. At the time he was seeing a girl named Tobi Vail of the band Bikini Kill and the line, "It is now my duty to completely drain you" was a phrase she said to Kurt and the time of their breakup. It's unclear whether she broke up with him or vice versa.
Interpretation #2: This is about Kurt Cobain's struggle with heroin: "I travel through a tube and end up in your infection" - The infection is the unreal world of heroin and the tube is simply the needle. "In a passionate kiss, from my mouth to yours" - The first "mouth" is the mouth of the needle. The second mouth is Kurt's vein, which is how the heroin is feeding him. "You're my vitamins" - Heroin was all he needed.
The band used a rubber duck, chains, and an aerosol can instead of guitars for the bridge.
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