This song is about the Cain and Abel story, which is the fourth chapter of the Book of Genesis in the Bible. Compare the lyrics to the events in the book, they are a clear match. In that story, Cain kills his brother Abel, committing the first murder on Earth.
The band's name comes from the same chapter in the Bible the inspired this song: Whoever slayeth Cain, vengeance shall be taken on him sevenfold This is God putting a mark on Cain so no others can harm him. But it's not benevolent: God wants to make him suffer. Yeah, the Bible is a great place to find themes for metal songs.
The song is part of the second Avenged Sevenfold album, Waking The Fallen, released in 2003. Their breakthrough came two years later when their video for "Bat Country" got support from an unlikely source: MTV's Total Request Live.
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