The Jetset Life Is Gonna Kill You

This song seems to be about drug use and maybe even suicide. The lyrics, "It gives the weak flight, it gives the blind sight" support this theory, as does "Lost in the prescription, she's got something else in mind."

A "Jetset Lifestyle" is a hedonistic pursuit involving lots of travel and is often characterized by drug use.

"Hotel Bella Muerte" means "The hotel of beautiful death." The hotel could be a place that the mind goes to temporarily. The lyrics, "Give up, get down, It's just the hardest part of living. Alright, she wants It all to come down this time" are saying that doing drugs and then coming back down again is a hard way to live, and someone, maybe his lover, wants him to come down and stay down for his own good.