The lyrics for the bleepy, trip-hoppy title track of Lady Gaga's third album are a contemplation on the crossing of art and pop culture. They find the New York songstress comparing a potential relationship between two people to the kinship between "art" and "pop." She croons: Come to me In all your glamour and cruelty Just do that thing that you do And I'll undress you Give it time Sometimes the simplest move is right The melody that you choose Can rescue you Producer White Shadow told MTV News the song was a defining moment during the making of ARTPOP: "I think 'Artpop' is definitive just because it is the title track," he said. "It's, like, one of the first ones she wrote. It's like the backbone of the record, right? It's what the record is about and, again, it kind of set up the stage to do different stuff."

Gaga explained the concept of the album during a Sirius XM special: "Every track on ARTPOP represents one adrenaline rush," she said. "Adrenaline of sex, adrenaline of art, adrenaline of fashion, adrenaline of drugs, etc."